The Science of Kambo

“Nature’s Vaccine”

The scientific and medical community has always been fascinated by medicines from the Amazon due to their power and effectiveness. Much research is still being done with the frog secretion and its capability, yet the scientific and medical community has not been able to repeat the results of Kambo in non-native construct.

The first western considerations of Kambo use, were made by a French priest, Father Constantin Tastevin, in 1925 while staying with the Kaxinawa tribe in Brazil. In the 1980’s an American anthropologist, Katherine Milton, observed Kambo use among the Mayoruna tribe in Brazil.

Italian Scientist and Nobel Peace Prize nominee, Vittorio Erspamer of the University of Rome was first to analyze Kambo in a laboratory in the 1980’s. He described that Phyllomedusa bicolor contains a “fantastic chemical cocktail with potential medical applications, unequaled by any other amphibian, a treasure trove of bioactive peptides.”

Different from countless other natural and pharmaceutical substances, Kambo has the facility to span the blood-brain barrier, allowing it to
penetrate significantly into the body. This allows Kambo to promote support to areas usually challenging to access and extremely powerful in treating dis-ease.

Kambo Peptides

Dermaseptin B2

Powerful antimicrobial activity against bacteria, yeast, fungi, Protozoa, and enveloped viruses that often cause infection. Research performed at the University of Paris has revealed this peptide to be effective at killing specific types of cancer cells.

Caerulein and Sauvagine

Interacts with the pituitary-adrenal axis and corticotropin (releasing receptors) involved in stress, anxiety, depression, and addictive behavior. Cause a fall in blood pressure accompanied by tachycardia. Promotes keen sensory perception, improves stamina, solid analgesic effect, boosts physical strength, and overall enhances the capability to regulate physical pain and stress.

Phyllokinin (bradykinins)

Focus on the bradykinin receptors. Relaxes smooth muscles. Potent vasodilator, increasing permeability of blood-brain barrier. Long lasting reduction in blood pressure.

Phyllomedusin (tachykinins)

Interacts with tachykinin receptors, regulates functions of dopamine, serotonin, and other neurotransmitters. Contracts smooth muscles. Potent vasodilator, increasing permeability of blood-brain barrier. Powerful effect on intestines and bowels, contributing to the purging of toxins.


Hypotension neuropeptide. Stimulates adrenal cortex and pituitary gland.


Stimulates the binding of agonists to A1 adenosine receptors. Antibiotic and antimicrobial peptide can reduce negative effects of a plethora of fungi, bacteria, and Protozoa, including cancer cells. Proposal for treating depression, stroke, seizures and cognitive loss aliments such as Alzheimer’s disease.


Opioid receptor agonists. Highest affinity and selectivity to delta opioid receptors of any natural compound. Powerful painkiller, 4000 times stronger than morphine.


Highly selective for mu opioid receptors and a powerful painkiller, 4000 times stronger than morphine and 40 times stronger than endogenic b-endorphines. Transforms the immune system, harmonizes the endocrine, digestive, and lymphatic system.


Potential in cardiovascular, inflammatory, and anti-cancer therapy. Helps remove the yeast, candida.

Kambo peptide research is presently being conducted with respect to:

  • Pain Relief
  • Depression
  • Anxiety
  • Digestive issues
  • Candida, mold, fungus
  • Chronic Fatigue
  • Migraines
  • Circulation issues
  • Cancer
  • Autoimmune Disease
  • Hepatitis + Herpes
  • Alzheimer’s
  • Parkinson’s
  • Skin and eye issues
  • Infertility
  • Endocrine Disease
  • Vascular insufficiency
  • Organ diseases

For the protection of Kambo and sustaining the legal accessibility of the medicine for practitioners, it is essential not to make medical claims. If you would like to do further research on the peptides found in Kambo please look to additional sources.
These statements have not been evaluated by the food and drug administration. This product or website is not intended to diagnose, treat, cure, or prevent any disease. Please consult your doctor.